Wednesday, March 19, 2008

Tenofovir has good concentrations and anti-HIV effect in semen

Tenofovir (Viread) rapidly suppresses HIV in semen and could help prevent the sexual transmission of HIV, according to a small study published in the March 1st edition of the Journal of Acquired Immune Deficiency Sydromes.

Levels of tenofovir in semen were several times those seen in blood. The risk of the sexual transmission of HIV is associated with the level of HIV in the male and female genital tract. There is also some evidence that the male genital tract acts as a “reservoir” for HIV, with the virus reproducing there independently to the blood .

Therefore, anti-HIV treatment that gets into the genital tract could reduce HIV viral load and the risk of transmission, and also the help reduce the risk of drug drug-resistant HIV developing.

Read the rest on aidsmap.

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