Showing posts with label Microbicides 2010. Show all posts
Showing posts with label Microbicides 2010. Show all posts

Tuesday, September 21, 2010

Still a long wait for HIV-approved protective gel

via South African Medical Journal, by Chris Bateman

June 2013 – that’s the ‘realistic’ date by which vulnerable South African women can expect to begin using an officially approved vaginal microbicide gel that would provide them with an unprecedented tool to protect themselves from HIV infection. This is the belief of biochemist and epidemiologist, Dr Quarraisha Abdool Karim, who, together with her clinician and fellow epidemiologist husband, Professor Salim Abdool Karim, led the now world-renowned ‘proof of concept’ trial of tenofovir vaginal gel to prevent HIV infection in women. In a 3-year study of 889 women in both rural and urban KwaZulu-Natal, they demonstrated a 39% reduction in HIV infection and a 51% reduction in genital herpes infection among women who used the gel (containing 1% of the antiretroviral (ARV), tenofovir).

Read more

To read even more on this subject see the IRMA blog from 7/27/10

Friday, June 4, 2010

Even More, More, More Microbicides 2010 Pics a la IRMA


Above pic a collage - courtesy of Katie West from the Global Campaign for Microbicides - documenting some of the activities at the Advocates Corner'.

Click here for more pics a la IRMA. 


Or you can watch the slide show on the left hand side of this blog.



Thursday, June 3, 2010

Six existing drug classes now being tested as microbicides

via Aidsmap, by Gus Cairns

"Rectal cells are more easily infected by HIV, a microbicide can make the most obvious difference to their vulnerability; it offers the most protection to the most easily-infected tissue cells, but makes less difference to less easily-infected tissue."



A number of presentations at the 2010 International Microbicides Conference in Pittsburgh concerned microbicide research using established classes of HIV drugs that have not been used as microbicides before.

Maraviroc had previously shown only modest anti-HIV activity as a microbicide. The current studies confirmed that its potency in preventing infection of cervical and penile tissue was relatively modest, unless the cells are already in an inflammatory state. The fact that, despite this, it protected monkeys from vaginal viral challenge suggests in might be a very potent rectal microbicide.

Read the rest.

Wednesday, June 2, 2010

Microbicides: the quest for user-friendly formulations



"Finally, a team have developed a vaginal microbicide as a film smaller than a stick of gum and as thin as a sheet of paper."


A large number of presentations at the Microbicides 2010 Conference in Pittsburgh documented the development of microbicides very different from gels or creams. Vaginal rings, quick-dissolve pills and thin films are all being tested.

Vaginal ring drug delivery

An intravaginal ring made from the plastic ethyl-vinyl acetate copolymer (EVA) and loaded with the two drugs dapivirine and maraviroc – already found to enhance each other’s potency - can deliver therapeutic levels of both drugs for as long as a month, according to test-tube studies. Fifteen days after being placed in a water/alcohol mixture, the ring was delivering half a gram of dapivirine and a gram of maraviroc per day.

Vaginal/rectal tablets

The tablet is ‘bioadhesive’ – this means the voluminous gel gets the drug delivered to all the mucous surfaces needed and then dissolves away. It also binds the drug to the mucous membranes, concentrating it at the surfaces needed and guaranteeing a consistent level of drug over 8-12 hours.

Quick-dissolve film

The film is made of a thin polyvinyl alcohol polymer, a water-soluble synthetic plastic used in multiple consumer and biomedical products, including contraceptive films, contact lens solutions and mouthwash strips.

Read the rest.

Monday, February 22, 2010

MARK IT DOWN - Microbicides 2010 Pre-Conference Workshop - with IRMA and others

Where: Pittsburgh, Pennsylvania

When: May 22, 2010

The Global Campaign for Microbicides (GCM), in close partnership with the African Microbicides Advocacy Group (AMAG), AVAC (Global Advocacy for HIV Prevention Research), and the International Rectal Microbicides Advocates (IRMA), will hold a day-long pre-conference workshop before the start of the official Microbicides 2010 Conference. The pre-conference workshop will feature seasoned advocates and researchers from the HIV prevention research field who will provide new and experienced advocates, community representatives, and trial staff with latest updates and previews on topics to be presented at the conference. An array of thematic skills-building sessions also will be conducted. The official opening ceremony of the Microbicides 2010 Conference will immediately follow the workshop at the David L. Lawrence Convention Center.

The Microbicides 2010 Pre-Conference Workshop will be held on Saturday, 22 May 2010. Please save the date and continue to check the GCM website for updates on the pre-conference location, program, and registration.

Hope you will join us!

Tuesday, February 9, 2010

Microbicides 2010 Announces Date Extensions for Early Reg, Late Breakers and More

PLEASE TAKE NOTE:

Given the ongoing extreme weather on the east coast of the United States these past several days the organizers of Microbicides 2010  have decided to revise the following dates:

     Notification of abstract and scholarship status: Monday 22nd February

     Late breaker submission: Thursday15th April

     Early registration deadline: Monday 1st March 

Friday, December 18, 2009

Microbicides 2010 Announces Deadline Extensions



Good News! There is still time to submit your abstract and scholarship application. All conference deadlines have been extended.

M2010 Key Date Extensions

January 22, 2010 at 6PM EST

    * Deadline for submission of scholarship applications and abstracts

February 12, 2010 at 6PM EST

    * Early registration ends

February 15, 2010 at 6pm est

    * Notification of scholarship awards and abstract acceptances

April 15, 2010 at 6PM EST

    * Deadline for submission of late breaker abstracts

Visit the M2010 website.

Thursday, December 17, 2009

Get inspired by Kadiri and help an IRMA advocate attend Microbicides 2010

Will you chip in?

TODAY - thanks to the generosity of the Elton John AIDS Foundation, and IRMA members, we already have $3,485 in our John Shaw Memorial Scholarship Fund to help support IRMA advocates attend the Microbicides 2010 conference coming up in Pittsburgh, May 2010.

We would like to bring that total to $10,000 - so we can help as many people as possible attend this important conference - and here is where you come in.

To donate to the John Shaw Memorial Scholarship fund, you may do so securely right here on this blog. In the upper left hand corner, there is a Chip In! box (just like the one right in this post) that allows you to donate whatever amount you would like via PayPal - securely.

The planners of M2010 are providing a large number of scholarships – so IRMA plans to fill in the gaps for rectal microbicide advocates who were unable to secure that support. We plan to release information on IRMA’s competitive scholarship process in early January 2009. Microbicides 2010 will be announcing their scholarships on February 1 – and IRMA will announce recipients of our support by March 1, 2010. IRMA scholarship recipients are required to have applied for M2010 support to be considered.

IRMA created the John Shaw Memorial Scholarship Fund in late 2007. John was a valued, enthusiastic and delightful member of the IRMA Steering Committee for over a year. He passed away Thursday, September 27, 2007. An LGBTQ/human rights advocate for over 20 years, John was also a Person With AIDS since at least 1990.

His fund helped rectal microbicide advocates attend the M2008 conference in New Delhi. Click here for a list of scholarship recipients, including Kadiri Audu of IRMA Nigeria, who went on to become Community Vice Chair of IRMA's Steering Commitee. He wrote about his Delhi/Microbicides 2008 conference for the IRMA blog - which we have republished below.

We hope he will inspire you to chip in - anything at all helps!

----------------------


Correspondence from IRMA advocates
by way of India

M2008 memories and the path forward

Taking rectal microbicide advocacy
to the next level in Lagos




by Kadiri Audu, Lagos. Nigeria
[read Kadiri's bio]

First, I want to thank the organizers of Microbicides 2008, IRMA, AIDS Foundation of Chicago and the John Shaw Memorial Scholarship fund that gave me the opportunity to attend the M2008 in New Delhi.

New Delhi is beautiful and the weather was just alright. I do not know if there is any better place to have hosted the conference in India, the conference was exciting and wonderful. It was interesting to have met new advocates from other parts of the world, and it was also interesting to know that people from the developed world like the USA and Canada are actually leading the research on rectal microbicides. Also, the Advocates Corner was a splendid idea because it gave the John Shaw Scholarship recipients, new advocates, and other IRMA members the chance to meet one another and build networking links among ourselves. My favorite memory was the chance to meet other advocates and the dinner organized for the conference participants.

I have been sharing my experience of the conference with members of the various networks that I belong to in our meetings. In addition to sharing my experience, I also share some materials that I collected at the advocates corner, i.e. stickers, pens and posters carrying the message about the conference.

In taking rectal microbicide advocacy to the next level, we have already formed Lagos IRMA, the aim is to mobilize more advocates in line with IRMA research and activities. We have even started e-mailing in that regards - our email address is lagosirma@yahoo.com, myself and Abdullrahaman formed it. He is also a new advocate that attended the conference and we operate from the same city. As of today we have 21 new members from our community.

Presently we are looking at reaching out to more people and groups like the youth leaders, the artisan groups like the hair dressers association, barbers association, the auto mechanic association, etc within our locality.

I would also like to suggest that we have training opportunities for us and our new members so as to be able to carry on the work effectively.

Thanks once again.
Kadiri Audu E

Wednesday, November 4, 2009

Send an IRMA Advocate to Pittsburgh!

Will you chip in?



by Roy Wadia, IRMA Steering Committee Member

I was one of the lucky recipients of the first round of John Shaw scholarships, to attend Microbicides 2008 in New Delhi. I'd been with IRMA (the former IRMWG) for a while by that time, and while I'd done a lot of HIV/AIDS advocacy and communications work during my time at WHO China and then at the BC CDC in Canada, I'd never really focused on microbicide issues until my introduction to this amazing group.

The more I delved into the subject matter, which initially seemed rather arcane, the more I realized its importance in the global response to the prevention and control of HIV/AIDS and STI. By focusing on rectal microbicides, an issue linked directly to the need to focus on anal sex and its role in the HIV/AIDS picture -- and yet one that is still not widely discussed or given its due in both scientific and advocacy circles -- IRMA and its membership has helped fill a conspicuous gap, prodding scientists, researchers and advocates alike.

The Delhi conference itself was an amazing chance to network, to meet some extraordinary individuals, and to experience that rather wonderful and long-overdue moment when the health minister of India, the conference host country, mentioned rectal microbicides as a weapon in the (if you'll pardon the unfortunate pun) arsenal to fight HIV/AIDS. It brought home the work that IRMA had been doing, and renewed our sense of mission and purpose. For this scholarship recipient it vindicated the work that's being done by so many of us, and I can only say that the John Shaw scholarship (named after a fearless advocate and lovely man) needs to continue and to be strengthened in the years to come.

-------------

IRMA created the John Shaw Memorial Scholarship Fund in late 2007. John was a valued, enthusiastic and delightful member of the IRMA Steering Committee for over a year. He passed away Thursday, September 27, 2007. An LGBTQ/human rights advocate for over 20 years, John was also a Person With AIDS since at least 1990.

His fund helped rectal microbicide advocates attend the M2008 conference in New Delhi. Click here for a list of scholarship recipients.

TODAY - thanks to the generosity of the Elton John AIDS Foundation, we already have $3,000 in the Fund to help support IRMA advocates to attend the Microbicides 2010 conference this coming May in Pittsburgh.

We would like to bring that total to $10,000 - and here is where you come in. Will you chip in to help a rectal microbicide advocate attend M2010?

To donate to the John Shaw Memorial Scholarship fund, you may do so securely right here on this blog. In the upper left hand corner, there is a Chip In! box that allows you to donate whatever amount you would like via PayPal - securely.

The planners of M2010 are providing a large number of scholarships – so IRMA plans to fill in the gaps for rectal microbicide advocates who were unable to secure that support. We plan to release information on IRMA’s competitive scholarship process in December 2009. Microbicides 2010 will be announcing their scholarships on February 1 – and IRMA will announce recipients of our support by March 1, 2010. IRMA scholarship recipients are required to have applied for M2010 support to be considered.

Thank you for your support!
Related Posts Plugin for WordPress, Blogger...