Thursday, June 12, 2008

IRMA Has a Dutch Love Affair!


IRMA is thrilled to see that information on rectal microbicides, IRMA's work and our report, Less Silence, More Science: Advocacy to Make Rectal Microbicides a Reality have been promoted on Homo HIV Plus, a Netherlands-based web site for HIV-positive gay men.

Homo HIV Plus also included the post on HIVNet, a Dutch web forum.

Lobby voor anaal gebruik microbiciden

Een recent gestarte internationale lobbygroep IRMA, International Rectal Microbicide Advocates, bepleit meer aandacht en fondsen voor de ontwikkeling van microbiciden voor gebruik bij kontneuken.

Het motto van IRMA is Less Silence, More Science: Advocacy to Make Rectal Microbicides a Reality. Microbiciden zijn vloeistoffen die in de vorm van een crème, gel of klysma in vagina of rectum kunnen bijdragen aan het voorkomen van hiv-overdracht...

To read the rest, follow this link.

Tuesday, June 10, 2008

"...we must admit that we are failing many, many people"


Speech by Mark Heywood for United Nations General Assembly on HIV/AIDS (UNGASS) civil society hearing on “Action for Universal Access 2010: Myths and Realities”


Click here for more info on the UNGASS 2008 High Level meeting

10 JUNE, 2008


Friends and comrades. Good morning.My theme is: Human Rights – do we believe in them and what if we do? My name is Mark Heywood. I am one of the leaders of the Treatment Action Campaign and the Deputy Chairperson of the SA National AIDS Council.

We are all equals in this meeting. We each have a responsibility for human rights. Some of you, particularly from government, have power and resources to better people’s lives. Some of you have little power, but come from communities whose rights are violated daily. But whether from government or civil society we must admit that we are failing many, many people. This is because in most parts of the world human rights violations that increase the risk of HIV infection, and those that follow after HIV infection are getting worse.

Hundreds of thousands of children still are being born with preventable HIV infection – hardly making them equal. People are dying of preventable illnesses. People are being confined in squalid prisons for drug resistant TB – with no concern for their dignity - in the name of ‘public health’. Woman and children are raped in frightening numbers. Rich people live with HIV -- and poor people die, usually after a period of added pain and indignity.

Regrettably – in China, Zimbabwe and other countries - many who fight for rights – or expose their violations - find themselves the victims of their governments or their self-serving officials. We call on China to free Hu Jia now. We have to ask: do our governments really believe in human rights? In the last 20 years nearly one third of UN Members have adopted new Constitutions, many of which explicitly protect human rights. But this legal commitment is meaningless unless these rights are given effect to. This is a duty of governments – not a choice. And it is the duty of civil society to hold governments up to the standards they have accepted on paper. Poor people cannot afford lip service to human rights from civil society either. When civil society is snared in endless conferences and flattered at “consultations” we become part of the problem. When we gratefully accept the hand-me-downs of government, we leave the poor and vulnerable, defen seless, and eventually very uncivil – as we have seen in the horrific xenophobic violence of South Africa that has displaced 50,000 people.

We say to civil society leaders: work with and assist your governments, but do not trust their promises. There is a direct link between the degree to which human rights are protected and your pressure on government and its institutions. We have learnt this from experience in South Africa. For example:

Despite our liberation, it took 14 years until a court eventually ordered our national defence force to end the mandatory exclusion of people with HIV from all positions.

In South Africa it takes pressure from community activists to get the police to investigate and the courts to effectively prosecute murder, rape and domestic violence.

In South Africa officials of my government (some probably sitting among you) still persecute doctors for carrying out WHO recommendations on the prevention of mother to child HIV transmission and reducing maternal mortality.

Unfortunately, human rights violations are the global reality, especially when people lack power and organization to fight back. Therefore civil society must recognize that human rights have to be demanded, fought for, won and then held onto. This can be done through systematic community organisation, demonstration, legal action, treatment and prevention literacy, human rights education and by demanding to be meaningfully involved at every level of policy-making.

To the democratic governments here today we say: recognise us as equals. Account to us. The response to HIV will be better for that. When you exclude us from planning or implementation, or dismiss our demands, you betray a solemn pact to govern with stalwart adherence to democratic principles, which are the foundation for respect, protection and fulfillment of human rights. Where governments are not democratic and suppress and torture us we call on the UN to end its policies of quiet diplomacy. This meeting must not make any more false promises. Human rights will not be realized if they are delivered in e-mailed Declarations from New York.

Finally this High Level Meeting must reconfirm the principle that Universal Access by will not be achieved without human rights. So we call on you to:

Demand an urgent increase in development aid to meet the commitments that have already been promised, particularly by OECD countries; This is not a favour to us, but a human rights duty.

Devise and implement systems that measure and monitor human rights;

Have the courage to openly denounce countries such as Zimbabwe that violate rights to health;

Demand investment in justice systems that poor people have access to.

Finally, end the distracting talk of AIDS ‘exceptionalism’. Every threat to life and dignity of poor people, be it through a disease or other causes, should generate an exceptional response. We call on the UN and the WHO not to relegate the response to AIDS to the level of your past failures, such as TB or your mute witness to the demise of our health systems. Instead, raise the response to other challenges to the level we seek to achieve with AIDS.

Good luck and thank you.

Meanwhile, in Brazil...

Brazilian President: Opposition to Homosexuality is a "Perverse Disease"

BRASILIA, Brazil, June 9, 2008 (LifeSiteNews.com) - June 5 was a landmark day for the international homosexual movement. For the first time in history, the president of a nation officially launched a conference with the sole purpose of promoting and defending the homosexual agenda.

Brazilian President Luiz Lula had the First National Conference of Gays, Lesbians, Bisexuals, Transvestites and Transsexuals (GLBT), inaugurated by presidential decree, and called for "a time of reparation" in Brazil.

Accompanied by six ministers, Lula exhorted all those opposed to the gay-rights movement to "open and purify their minds." Lula then announced his complete support for the homosexual movement, saying that he is "going to do all that is possible so that the criminalization of homophobia and the civil union may be approved."

After calling for a universal embrace of the homosexual movement, the president affirmed that "homophobia" is perhaps "the most perverse disease impregnated in the human head."

Read the rest.

Monday, June 9, 2008

The Global Mapping of Pleasure - for you!

[Thanks to IRMA member Jo Robinson for sending this to us! It is a fantastic document.]

The Global Mapping of Pleasure is a collection of practical, conceptual and inspiring case studies of individuals and organizations around the world who aim to empower people by eroticizing safer sex and making sex education sexy. It is intended for a wide audience, including:

• sex educators

• sexual and reproductive health organizations

• medical personnel and those working in reproductive health clinics

• people and organizations focused on HIV prevention, and HIV and AIDS treatment and care

• researchers and academics

• donors and governments

• people and companies that produce erotic media, such as porn films and magazines, and those
working in mainstream media

• everyone who is tired of hearing the same-old prevention messages – that sex is dangerous, something to be feared, and that safer sex is un-sexy

• anyone looking for a new, exciting and sexy approach to safer sex and sexual health.

Click here to download the PDF

Preclinical evaluation of lime juice as a topical microbicide candidate

For the full article: http://www.retrovirology.com/content/5/1/3

Abstract

Background
The continued growth of the global HIV epidemic highlights the urgent need to develop novel prevention strategies to reduce HIV transmission. The development of topical microbicides is likely to take a number of years before such a product would be widely available. This has resulted in a call for the rapid introduction of simpler vaginal intervention strategies in the interim period. One suggested practice would be vaginal douching with natural products including lime or lemon juice. Here we present a comprehensive preclinical evaluation of lime juice (LiJ) as a potential intervention strategy against HIV.

Results
Pre-treatment of HIV with LiJ demonstrated direct virucidal activity, with 10% juice inactivating the virus within 5 minutes. However, this activity was significantly reduced in the presence of seminal plasma, where inactivation required maintaining a 1:1 mixture of neat LiJ and seminal plasma for more than 5 minutes. Additionally, LiJ demonstrated both time and dose-dependent toxicity towards cervicovaginal epithelium, where exposure to 50% juice caused 75–90% toxicity within 5 minutes increasing to 95% by 30 minutes. Cervicovaginal epithelial cell monolayers were more susceptible to the effects of LiJ with 8.8% juice causing 50% toxicity after 5 minutes. Reconstructed stratified cervicovaginal epithelium appeared more resilient to LiJ toxicity with 30 minutes exposure to 50% LiJ having little effect on viability. However viability was reduced by 75% and 90% following 60 and 120 minutes exposure. Furthermore, repeat application (several times daily) of 25% LiJ caused 80–90% reduction in viability.

Conclusion
These data demonstrate that the virucidal activity of LiJ is severely compromised in the presence of seminal plasma. Potentially, to be effective against HIV in vivo, women would need to apply a volume of neat LiJ equal to that of an ejaculate, and maintain this ratio vaginally for 5–30 minutes after ejaculation. Data presented here suggest that this would have significant adverse effects on the genital mucosa. These data raise serious questions about the plausibility and safety of such a prevention approach.
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