Wednesday, May 23, 2012

AIDSmeds: Rectal Microbicide Shows Better Safety in Laboratory Study

via AIDSmeds

Laboratory testing of a modified version of the Viread (tenofovir) microbicide gel provides further evidence that it may be safe for rectal use, according to a paper published online ahead of print by the Journal of Antimicrobial Chemotherapy.

The encouraging results contribute to a better understanding of the gel’s tolerability, already evident in preliminary findings from a 65-person Phase I clinical trial reported at the 19th Conference on Retroviruses and Opportunistic Infections earlier this year in Seattle.

“The lining of the rectum is much more fragile than the vaginal epithelium, so we can’t be certain a product like tenofovir gel that is safe for vaginal use will be completely safe to use in the rectum,” said lead study author Charlene Dezzutti, PhD, of the University of Pittsburgh School of Medicine and the Microbicide Trials Network (MTN) in an accompanying news announcement. “We are very encouraged by our laboratory data that suggest the reformulated gel could be safer for rectal use, and serve as a dual compartment gel for use in both the vagina and rectum.”

Read the rest.

-------------------

*Join IRMA's robust, highly-active. moderated, global listserv addressing rectal microbicide research and advocacy as well as other interesting new HIV prevention technologies by contacting us at rectalmicro@gmail.com. Joining our listserv automatically makes you a member of IRMA - a network of more than 1,100 advocates, scientists, policy makers and funders from all over the world.

*Please look for us on Facebook: www.facebook.com/InternationalRectalMicrobicideAdvocates, and you can follow us on Twitter: @rectalmicro.

*Also, please note that shared news items from other sources posted on this blog do not necessarily mean IRMA has taken any position on the article's content.

-------------------

No comments:

Related Posts Plugin for WordPress, Blogger...