A new Northwestern Medicine study will undertake a bold new protocol to completely eradicate latent HIV cells that current drugs don't affect. Participants, with diagnosed HIV, in the experimental group will be given an investigational HIV vaccine that actually wakes up dormant cells at the same time regular HIV-drug therapy is aimed at extinguishing the activated cells.
“If we can effectively decrease the reservoir then we can think about curing HIV," said Robert Murphy, M.D., founding director of Northwestern University Feinberg School of Medicine’s Center for Global Health and an infectious disease physician at Northwestern Memorial Hospital.
Many people with HIV are living with nearly undetectable levels of the virus in their blood, but they can’t entirely clear HIV out of their bodies with the current treatment regimens. Dormant HIV cells linger, hiding in the body and resisting the powerful benefits of anti-HIV drugs. Through the study, called EraMune 02, researchers at Feinberg’s Center for Global Health plan to activate dormant HIV cells, fight them off and kill the virus.
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